KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
12.73
Human Site:
T250
Identified Species:
21.54
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
T250
V
T
P
N
S
G
G
T
P
F
S
Q
D
T
A
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
T241
V
G
T
P
G
N
G
T
P
C
S
Q
D
T
S
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
Dog
Lupus familis
XP_543382
1925
209302
T250
V
T
P
N
S
G
G
T
P
F
S
Q
D
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
T249
V
T
P
N
S
G
G
T
P
F
S
Q
D
T
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
Chicken
Gallus gallus
Q5F3P8
2008
223067
D268
S
S
T
P
F
S
H
D
T
A
Y
S
S
C
R
Frog
Xenopus laevis
Q66J90
1938
216239
Y268
P
F
S
H
D
T
A
Y
S
S
S
R
Q
G
T
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
M285
P
S
G
T
N
T
P
M
S
L
D
T
A
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
P206
L
I
G
P
K
V
T
P
Q
W
T
F
Q
Q
A
Honey Bee
Apis mellifera
XP_395451
1406
159180
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
V73
E
R
I
K
R
T
G
V
R
K
T
S
E
N
M
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
E240
D
P
Q
F
Q
M
P
E
Q
P
S
Q
Q
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
53.3
0
100
N.A.
100
N.A.
N.A.
0
0
6.6
0
N.A.
6.6
0
6.6
13.3
P-Site Similarity:
100
60
0
100
N.A.
100
N.A.
N.A.
0
6.6
20
20
N.A.
26.6
0
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
8
0
0
8
0
29
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% C
% Asp:
8
0
0
0
8
0
0
8
0
0
8
0
29
8
0
% D
% Glu:
8
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% E
% Phe:
0
8
0
8
8
0
0
0
0
22
0
8
0
0
0
% F
% Gly:
0
8
15
0
8
22
36
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
8
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
15
% M
% Asn:
0
0
0
22
8
8
0
0
0
0
0
0
0
8
0
% N
% Pro:
15
8
22
22
0
0
15
8
29
8
0
0
0
0
0
% P
% Gln:
0
0
8
0
8
0
0
0
15
0
0
36
22
8
0
% Q
% Arg:
0
8
0
0
8
0
0
0
8
0
0
8
0
0
8
% R
% Ser:
8
15
8
0
22
8
0
0
15
8
43
15
8
0
15
% S
% Thr:
0
22
15
8
0
22
8
29
8
0
15
8
0
29
8
% T
% Val:
29
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _